Fazlur Rahman

Background: Chronic coronary syndrome (CCS) is a common clinical manifestation of coronary artery disease (CAD) resulting from an imbalance between myocardial oxygen supply and demand, most often due to atherosclerotic obstruction. Serum gamma-glutamyl transferase (GGT), a biomarker of oxidative stress, has been implicated in the pathogenesis of atherosclerosis and may correlate with the severity of CAD. Objective: To evaluate the relationship between serum GGT levels and the angiographic severity of CAD in patients with CCS. Methods: This cross-sectional observational study was conducted in the Department of Cardiology, Bangladesh Medical University (BMU), formerly known as Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, from October 2019 to September 2020. A total of 50 patients with CCS who underwent coronary angiography were included. Participants were divided into two groups: Group A (25 patients with severe CAD, Gensini score ≥36) and Group B (25 patients with normal coronary arteries, Gensini score <36). Serum GGT levels were measured in the Department of Biochemistry, and angiographic severity was assessed using the Gensini scoring system. Statistical analyses were performed using Statistical Product and Service Solutions (SPSS, version 23.0; IBM SPSS Statistics for Windows, Armonk, NY). Results: The mean serum GGT level was significantly higher in Group A (64.28 ± 14.36 U/L) than in Group B (32.80 ± 5.04 U/L) (p = 0.001). A strong positive correlation was found between GGT level and both the number of affected vessels (r = 0.758, p = 0.001) and the Gensini score (r = 0.923, p = 0.001), indicating that higher GGT levels were associated with greater angiographic severity of CAD. Conclusion: Serum GGT level showed a significant positive correlation with the angiographic severity of CAD in patients with CCS, suggesting its potential role as a biomarker for disease severity and risk stratification.

Prosecutors accuse him of contempt of court for allegedly maligning the tribunal on television following the verdict against Sheikh Hasina

Objectives This study aims to identify factors associated with early antenatal care (ANC) initiation using a survival analysis approach applied to nationally representative data. Design, setting and participants This study used a cross-sectional design based on data from the nationally representative 2022 Bangladesh Demographic and Health Survey. The survey was conducted at the community level across all administrative divisions of Bangladesh. A total of 5128 ever-married women aged 15–49 years who had a live birth within 5 years prior to the survey were included in the analysis. Women with missing or incomplete information regarding the timing of their first ANC visit were excluded from the study. Outcome The primary outcome was early initiation of ANC, defined as the first ANC contact within the first trimester. Materials and methods The study applied survival analysis methods, including Kaplan-Meier survival curves, log-rank tests and an Accelerated Failure Time model, to assess the determinants of early ANC initiation. Findings Only 37.9% (95% CI 36.0% to 39.9%) of women in Bangladesh initiated ANC within the first trimester. Early ANC initiation was associated with higher maternal age, education, skilled employment, wealthier households, media exposure, higher decision-making autonomy, higher husband’s education and urban residence. Women who reported that distance to a health facility was not a big problem had initiated ANC earlier than those who considered distance a major barrier. Regional disparities were also evident, with women from Barishal, Chattogram, Rajshahi, Khulna and Rangpur accessing ANC later than those in Dhaka. Conclusions Persistent inequalities in early ANC initiation highlight the need for targeted policies to reduce financial barriers, improve healthcare accessibility and strengthen awareness campaigns to ensure equitable maternal healthcare in Bangladesh. Data are available in a public, open access repository. The datasets used in this study are owned by the Demographic and Health Surveys (DHS) Program. These data are available on request and approval from .

Nothing is more personal than illness and healing. So medical memoirs are not monolithic, and are written by doctors, patients, the loved ones of the sufferers, and others. The eight memorable memoirs here, from the past to the present, the best ones I believe, consist of writers of different racial and economic backgrounds, genders, and faiths.

Abstract Background Snakebite is a neglected tropical disease with significant public health implications, especially in rural Bangladesh.