Manoj Nair

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VDI is an acronym for “ Virtual Desktop Infrastructure ,” which enables users to access a working computer remotely from any device, such as a laptop, tablet, or smartphone, through an internet connection.

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Early postoperative endoscopic evaluation after repair of a perforated gastroduodenal ulcer is rarely performed due to concerns regarding disruption of the surgical closure. We report a patient who underwent primary sutured repair with omental reinforcement for a prepyloric ulcer perforation and subsequently developed postoperative anemia without an identifiable source of bleeding. Initial imaging, including computed tomography angiography, revealed no evidence of active arterial bleeding, prompting a carefully planned endoscopic evaluation in the third postoperative week. Endoscopy demonstrated an intact suture line with healthy granulation tissue and visible intraluminal Vicryl sutures, without evidence of bleeding or dehiscence. This case highlights that early postoperative endoscopic assessment can be safely performed when clinically indicated and provides valuable insight into the intraluminal healing process following oversewn ulcer perforation repair.

AI is expanding attack surfaces and empowering relentless attackers. Learn why continuous offensive security and independent validation are now essential.

Cambridge Scientists Solve Mystery of Brain Switch Behind Two Opposite Weight-Loss Drug Types

SAN DIEGO — Privacy-focused search engine DuckDuckGo sol d out its first-ever eyewear line within days of launch in late July, a satirical pair of

KHANDWA, Madhya Pradesh — A video shared widely on social media Tuesday shows a man dressed head-to-toe in a dog costume walking into a public

Background Venous thromboembolism (VTE) is a preventable cause of hospital-associated morbidity and mortality. In emergency general surgery, timely prophylaxis can be challenging because decisions regarding bleeding risk and urgent procedures must be balanced against the need for prompt pharmacological prophylaxis. This study quantified time to first pharmacological prophylaxis and compared VTE prevention processes across two sequential emergency general surgery cohorts. Methods We conducted a single-centre retrospective cohort study of adult emergency general surgical admissions across two predefined inpatient cohorts assessed approximately one month apart and separated by implementation of a targeted thromboprophylaxis practice change. Patient-level electronic prescribing and medication-administration records were used to measure time from admission to first low-molecular-weight heparin (LMWH) administration among patients for whom pharmacological prophylaxis was appropriate and a first administration time was assessable, and to evaluate VTE risk assessment, dose appropriateness, mechanical prophylaxis, and other process measures. Duplicate carry-over records, an elective admission, and records predating the implementation cutoff were excluded from the primary comparison. Categorical outcomes were compared using Fisher's exact test and continuous variables using the Mann-Whitney U test. Results Seventy-two emergency admissions were included (42 in the earlier cohort and 30 in the later cohort). Among patients with an assessable first LMWH administration time, the median admission-to-first-LMWH interval decreased from 20.8 hours (IQR: 13.9-27.9) to 16.4 hours (IQR: 10.5-21.5; p = 0.120), while administration within 14 hours increased from 8/32 (25.0%) to 9/24 (37.5%; p = 0.384). Correct completion of the electronic VTE risk-factor form increased from 8/42 (19.0%) to 26/30 (86.7%), an absolute increase of 67.6 percentage points (95% CI: 50.6-84.6; p < 0.001). Mechanical prophylaxis prescribing increased from 33/42 (78.6%) to 30/30 (100%; p = 0.008). Overall composite compliance did not change significantly. Conclusions In this retrospective cohort study, time to first LMWH administration improved numerically but remained frequently beyond the 14-hour threshold. Electronic VTE risk documentation and mechanical prophylaxis prescribing improved substantially in the later cohort. The findings identify a persistent gap between VTE assessment and timely pharmacological prophylaxis, highlighting medication-delivery processes as an important area for further evaluation and quality improvement in emergency general surgery.