Sarah Long

Cruisers Yachts, a premier American manufacturer of luxury yachts and a wholly owned subsidiary of MarineMax, Inc. (NYSE: HZO), the world’s largest recreatio...

Manganese intoxication has been described in children on long term parenteral nutrition presenting with liver and nervous system disorders. Cases are reported of a brother and sister on long term parenteral nutrition with hypermanganesaemia and basal ganglia manganese deposition, detected by magnetic resonance imaging (MRI), without overt neurological signs. Following reduction of manganese intake, basal ganglia manganese was monitored by repeated MRI, and neurological and developmental examinations. An MRI intensity index of the globus pallidus declined over a three year period from 0.318 and 0.385 to 0.205 and 0.134 with concomitant falls in whole blood manganese from 323 and 516 to 226 and 209 nmol/l (normal range, 73–210 nmol/l). Unlike adult experience these children developed normally without neurological signs. In conclusion, deposited manganese is removed from neural tissue over time and the prognosis is good when neurological manifestations and liver disease are absent.

American folk band Big Thief have announced a surprise concert in Dolan's at the end of April. Presale tickets go on sale this evening.

This revival of an early Anton Chekhov play could be significantly improved by simply adding a few furnishings. Jiyoun Chang, best known as a lighting designer, takes on the scenic design here, too, and her approach makes any revival of Waiting for Godot look overdecorated. The first act, set in the title character's garden, features a single bench; the second act, taking place in a drawing room, has nothing but a carpet. Thus, a group of people must play cards standing up. Later, two of them lie down; who can blame them? Everyone needs a break now and then.